Salicylaldehyde → Methyl (2E)-3-(2-hydroxyphenyl)-2-propenoate

HRID 1870570Notes

Reaction equation

HRID 1870570 reaction equation
[CH3:1][O:2][C:3](=[O:14])/[C:4](/C)=[CH:5]/[C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[OH:12].COC(=O)C=P(C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1.C(=O)C1C(=CC=CC=1)O>>[CH3:1][O:2][C:3](=[O:14])/[CH:4]=[CH:5]/[C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[OH:12]

Participants

4

Reactant 3

HCID 6998SalicylaldehydeHCID 17453Acetic acid, 2-(triphenylphosphoranylidene)-, methyl esterHCID 21490383HCID 21490383, compound

Product 1

HCID 5370693Methyl (2E)-3-(2-hydroxyphenyl)-2-propenoate

Procedure

According to the procedure of Example 1, (E)-3-(2-hydroxy-phenyl)-2-methyl-acrylic acid methyl ester was prepared from methyl(triphenyl-phosphoranylidene)acetate and salicylaldehyde.

Sources & evidence

ORD record
ord-35a34a52f4aa4ea882bcaf2926d607cc
Source dataset
uspto-grants-2000_08
Patent number
US06096918

Reaction notes

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