Sodium Carbonate → HCID 18692816, compound

HRID 1870681Notes

Reaction equation

HRID 1870681 reaction equation
[OH:1][CH2:2][CH2:3][CH2:4][N:5]([CH2:12][CH2:13][CH2:14][OH:15])[C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1.[N:16]([O-])=[O:17].[Na+].C(=O)([O-])[O-].[Na+].[Na+]>Cl.O>[OH:1][CH2:2][CH2:3][CH2:4][N:5]([CH2:12][CH2:13][CH2:14][OH:15])[C:6]1[CH:11]=[CH:10][C:9]([N:16]=[O:17])=[CH:8][CH:7]=1

Participants

6

Reactant 3

HCID 10340Sodium CarbonateHCID 10846090HCID 10846090, compoundHCID 23668193Sodium Nitrite

Product 1

HCID 18692816HCID 18692816, compound

Reagents, catalysts & solvents 2

HCID 313Hydrochloric AcidSolventHCID 962WaterSolvent2×

Procedure

N,N-bis(3-hydroxypropyl) aniline (10.46 g) was dissolved in hydrochloric acid (20cm3) at 0-5° C. and sodium nitrite (3.45 g) in water(15cm3) was added dropwise. The mixture was stirred for 1 hr, water (10cm3) was added, made alkaline with sodium carbonate, separated in to an oil and water layer. The oil was dissolved in dichloromethane and the solvent removed to leave N,N-bis(3-hydroxypropyl)4-nitrosoaniline as a yellow solid.

Workup

  1. customseparated in to an oil and water layer
  2. dissolutionThe oil was dissolved in dichloromethane
  3. customthe solvent removed

Sources & evidence

ORD record
ord-d5311446c34f4549b6c81edd3d7768f0
Source dataset
uspto-grants-2000_08
Patent number
US06099625

Reaction notes

Loading…