Ethanol → 4-(4-(Pyridin-3-yl)-1H-imidazol-1-yl)butan-1-amine

HRID 1871036Notes

Reaction equation

HRID 1871036 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([C:7]2[N:8]=[CH:9][N:10]([CH:12](CC)[CH2:13]N3C(=O)C4C(=CC=CC=4)C3=O)[CH:11]=2)[CH:2]=1.O.[NH2:28]N.[CH2:30](O)[CH3:31]>>[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([C:7]2[N:8]=[CH:9][N:10]([CH2:12][CH2:13][CH2:30][CH2:31][NH2:28])[CH:11]=2)[CH:2]=1

Participants

4

Reactant 3

HCID 702EthanolHCID 24654Hydrazine hydrate (1:1)HCID 186948072-(4-(3-pyridinyl)-1H-imidazol-1-yl)-butyl-1H-iso-indol-1,3(2H)-dione

Product 1

HCID 110421604-(4-(Pyridin-3-yl)-1H-imidazol-1-yl)butan-1-amine

Procedure

Using the procedure of Stage B of Example 1, 1.66 g of the product of Stage A and 0.46 ml of hydrazine hydrate in 30 ml of ethanol were reacted to obtain 936 mg of the desired product which was used as is for the synthesis.

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-bbe848dded124a9bb9282cb9a3de561e
Source dataset
uspto-grants-2000_08
Patent number
US06100404

Reaction notes

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