Salicylic Acid → Salicylic Acid

HRID 1871179Notes

Reaction equation

HRID 1871179 reaction equation
[C:1]([OH:10])(=[O:9])[C:2]1[C:3](=[CH:5][CH:6]=[CH:7][CH:8]=1)[OH:4].C([O-])(=O)C1C(=CC=CC=1)O.[Na+].[Na].[Cl-].[Zn+2:24].[Cl-]>>[Zn:24].[C:1]([OH:10])(=[O:9])[C:2]1[C:3](=[CH:5][CH:6]=[CH:7][CH:8]=1)[OH:4]

Participants

6

Reactant 4

HCID 338Salicylic Acid2×HCID 3007855ZincchlorideHCID 5360545SodiumHCID 16760658Sodium Salicylate

Product 2

HCID 338Salicylic AcidHCID 23994Zinc

Procedure

The aforementioned metallic salt of salicylic acid derivative can be easily synthesized by the method described in CLARK, J, L, Kao, H(1948) J. Amer. Chem. Soc. 70,2151. For instance, 2 moles of sodium salicylate (or a sodium salt of a salicylic acid derivative) and 1 mole of zinc chloride are added to a solvent and mixed. The thus obtained mixture is heated with stirring, thereby obtaining a zinc salt of a salicylic acid.

Workup

  1. additionmixed
  2. temperatureThe thus obtained mixture is heated

Sources & evidence

ORD record
ord-e37b4b42375e4834afc2654fff8164e1
Source dataset
uspto-grants-2000_08
Patent number
US06103441

Reaction notes

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