Ethanol → 3-[3-(2-Phenylimidazol-1-ylmethyl)phenyl]-5-iso-butyl-N-tert-butylthiophene-2-sulfonamide
Reaction equation
[Br:1][c:2]1[n:3]([CH2:7][c:8]2[cH:9][c:10](-[c:14]3[c:15]([S:23](=[O:24])(=[O:25])[NH:26][C:27]([CH3:28])([CH3:29])[CH3:30])[s:16][c:17]([CH2:19][CH:20]([CH3:21])[CH3:22])[cH:18]3)[cH:11][cH:12][cH:13]2)[cH:4][cH:5][n:6]1.[CH3:42][c:43]1[cH:44][cH:45][cH:46][cH:47][cH:48]1.[CH3:49][CH2:50][OH:51].[CH3:52][CH2:53][O:54][C:55]([CH3:56])=[O:57].[Na+:41].[OH-:40].[c:31]1([B:37]([OH:38])[OH:39])[cH:32][cH:33][cH:34][cH:35][cH:36]1.[cH:58]1[cH:59][cH:60][c:61]([P:62]([Pd:63]([P:64]([c:65]2[cH:66][cH:67][cH:68][cH:69][cH:70]2)([c:71]2[cH:72][cH:73][cH:74][cH:75][cH:76]2)[c:77]2[cH:78][cH:79][cH:80][cH:81][cH:82]2)([P:83]([c:84]2[cH:85][cH:86][cH:87][cH:88][cH:89]2)([c:90]2[cH:91][cH:92][cH:93][cH:94][cH:95]2)[c:96]2[cH:97][cH:98][cH:99][cH:100][cH:101]2)[P:102]([c:103]2[cH:104][cH:105][cH:106][cH:107][cH:108]2)([c:109]2[cH:110][cH:111][cH:112][cH:113][cH:114]2)[c:115]2[cH:116][cH:117][cH:118][cH:119][cH:120]2)([c:121]2[cH:122][cH:123][cH:124][cH:125][cH:126]2)[c:127]2[cH:128][cH:129][cH:130][cH:131][cH:132]2)[cH:133][cH:134]1>>[c:2]1(-[c:31]2[cH:32][cH:33][cH:34][cH:35][cH:36]2)[n:3]([CH2:7][c:8]2[cH:9][c:10](-[c:14]3[c:15]([S:23](=[O:24])(=[O:25])[NH:26][C:27]([CH3:28])([CH3:29])[CH3:30])[s:16][c:17]([CH2:19][CH:20]([CH3:21])[CH3:22])[cH:18]3)[cH:11][cH:12][cH:13]2)[cH:4][cH:5][n:6]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-63ab1b4b7cb04889a13b0c90e8f1eb15
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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