Methyl iodide → HCID 68590834, compound

HRID 1875338Notes

Reaction equation

HRID 1875338 reaction equation
[CH3:1][C:2]1[C:7]2[S:8][CH:9]=[CH:10][C:6]=2[CH2:5][CH2:4][N:3]=1.[CH3:11][I:12]>C(OCC)(=O)C>[I-:12].[CH3:11][N+:3]1[CH2:4][CH2:5][C:6]2[CH:10]=[CH:9][S:8][C:7]=2[C:2]=1[CH3:1]

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 57423976Thieno[2,3-c]pyridine, 4,5-dihydro-7-methyl- (5CI)

Product 1

HCID 68590834HCID 68590834, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

A mixture of 4.64 g (31 mmol) 7-methyl-4,5-dihydro-thieno[2,3-c]pyridine (prepared analogously to J.Am.Chem.Soc., 1951, 1257), 8.0 ml (128 mmol) methyl iodide and 20 ml of ethyl acetate is stirred for 15 min. The precipitate formed is suction filtered, washed with ethyl acetate and dried in vacuo.

Workup

  1. customprepared analogously to J.Am.Chem.Soc
  2. customThe precipitate formed
  3. filtrationfiltered
  4. washwashed with ethyl acetate
  5. customdried in vacuo

Sources & evidence

ORD record
ord-0843bf2fcfc94ff0ada02d33864cdc05
Source dataset
uspto-grants-2012_11
Patent number
US08309542B2

Reaction notes

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