Ammonia → HCID 86761682, compound

HRID 1878671Notes

Reaction equation

HRID 1878671 reaction equation
C([N:20]1[CH:24]=[C:23]([C:25]2[CH:26]=[CH:27][C:28]([O:31][C@@H:32]3[CH:39]4[CH2:40][N:35]5[CH2:36][CH:37]([CH2:41][CH:33]3[CH2:34]5)[CH2:38]4)=[N:29][CH:30]=2)[CH:22]=[N:21]1)(C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1.N.[ClH:43]>>[ClH:43].[NH:21]1[CH:22]=[C:23]([C:25]2[CH:26]=[CH:27][C:28]([O:31][C@@H:32]3[CH:39]4[CH2:40][N:35]5[CH2:36][CH:37]([CH2:41][CH:33]3[CH2:34]5)[CH2:38]4)=[N:29][CH:30]=2)[CH:24]=[N:20]1

Participants

4

Reactant 3

HCID 222AmmoniaHCID 313Hydrochloric AcidHCID 86621420HCID 86621420, compound

Product 1

HCID 86761682HCID 86761682, compound

Procedure

Prepared from the product of Example 114A (44.4 mg, 0.080 mmol) according to Method J: 1H NMR (300 MHz, methanol-D4) δ ppm 1.93-1.97 (m, 2H), 2.21 (br s, 1H), 2.36-2.41 (m, 2H), 2.57 (br s, 2H), 3.58 (br s, 2H), 3.66-3.75 (m, 4H), 5.45 (t, J=3.2 Hz, 1H), 7.12 (d, J=9.1 Hz, 1H), 8.13 (dd, J=8.6, 2.5 Hz, 1H), 8.25 (s, 2H), 8.47 (d, J=1.7 Hz, 1H). MS (DCI/NH3) m/z=297 (M+H)+. Anal. Calcd. for C17H20N4O.2 HCl.1.15H2O: C, 52.11; H, 6.30; N, 14.30. Found: C, 52.14; H, 6.33; N, 14.24.

Sources & evidence

ORD record
ord-89d6eb9b30f44d19af1ef74daa516c89
Source dataset
uspto-grants-2012_11
Patent number
US08314119B2

Reaction notes

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