Sodium Hydroxide → HCID 86633439, compound

HRID 1881178Notes

Reaction equation

HRID 1881178 reaction equation
[CH2:1]([O:8][C:9]1[CH:14]=[CH:13][C:12](/[CH:15]=[C:16]2/[C:17](=[O:22])NC(=S)[S:20]/2)=[CH:11][C:10]=1[O:23][CH3:24])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[OH-:25].[Na+]>Cl>[CH2:1]([O:8][C:9]1[CH:14]=[CH:13][C:12](/[CH:15]=[C:16](\[SH:20])/[C:17]([OH:25])=[O:22])=[CH:11][C:10]=1[O:23][CH3:24])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 1268893HCID 1268893, compound

Product 1

HCID 86633439HCID 86633439, compound

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Conditions

Temperature
10 °C

Procedure

5-[1-(4-Benzyloxy-3-methoxy-phenyl)-meth-(Z)-ylidene]-2-thioxo thiazolidin-4-one (38 g) and 2.5M NaOH were warmed at 80° C. for one hour. Next the solution was cooled to 10° C. and poured slowly into 6M HCl-solution (200 ml). The reaction mixture was stirred at room temperature for one hour. The solid was filtered, washed with water and dried under vacuum.

Workup

  1. filtrationThe solid was filtered
  2. washwashed with water
  3. customdried under vacuum

Sources & evidence

ORD record
ord-3559c275e1fb4b54bca77f37c46507ee
Source dataset
uspto-grants-2012_11
Patent number
US08318785B2

Reaction notes

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