Hydrochloric Acid → HCID 15983234, compound

HRID 1881220Notes

Reaction equation

HRID 1881220 reaction equation
[CH3:1][O:2][C:3]([C:5]1[S:9][C:8]2[C:10]([O:20]CC)=[C:11]([O:17]CC)[C:12]([N+:14]([O-:16])=[O:15])=[CH:13][C:7]=2[CH:6]=1)=[O:4].Cl>[Cl-].[Zn+2].[Cl-].O>[CH3:1][O:2][C:3]([C:5]1[S:9][C:8]2[C:10]([OH:20])=[C:11]([OH:17])[C:12]([N+:14]([O-:16])=[O:15])=[CH:13][C:7]=2[CH:6]=1)=[O:4]

Participants

5

Reactant 2

HCID 313Hydrochloric AcidHCID 67094366HCID 67094366, compound

Product 1

HCID 15983234HCID 15983234, compound

Reagents, catalysts & solvents 2

HCID 3007855ZincchlorideCatalystHCID 962WaterSolvent

Conditions

Temperature
100 °C

Procedure

6,7-Diethoxy-5-nitro-benzo[b]thiophene-2-carboxylic acid methyl ester (0.77 g), zinc chloride (5.0 g) and conc. HCl (1.3 ml) were mixed and heated at 100° C. for 2 hours. The reaction mixture was cooled. Water (20 ml) was added and the precipitate was filtered. The crude product was recrystallized twice from methanol.

Workup

  1. temperatureThe reaction mixture was cooled
  2. filtrationthe precipitate was filtered
  3. customThe crude product was recrystallized twice from methanol

Sources & evidence

ORD record
ord-d7ea2a0aa20241fab83ec0e2d91fc7a9
Source dataset
uspto-grants-2012_11
Patent number
US08318785B2

Reaction notes

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