4-Chlorobenzaldehyde → 4-[2-(4-Chloro-phenyl)-vinyl]-1-nitro-benzene

HRID 1884160Notes

Reaction equation

C(OP([CH2:9][C:10]1[CH:15]=[CH:14][C:13]([N+:16]([O-:18])=[O:17])=[CH:12][CH:11]=1)(=O)OCC)C.[Cl:19][C:20]1[CH:27]=[CH:26][C:23]([CH:24]=O)=[CH:22][CH:21]=1>>[Cl:19][C:20]1[CH:27]=[CH:26][C:23]([CH:24]=[CH:9][C:10]2[CH:11]=[CH:12][C:13]([N+:16]([O-:18])=[O:17])=[CH:14][CH:15]=2)=[CH:22][CH:21]=1

Participants

Reactant 2

HCID 77264-Chlorobenzaldehyde

HCID 256065Diethyl 4-nitrobenzylphosphonate

Product 1

HCID 1554154-[2-(4-Chloro-phenyl)-vinyl]-1-nitro-benzeneYield 95%

Procedure

Prepared in analogy to example 56b) from (4-nitro-benzyl)-phosphonic acid diethyl ester and 4-chloro-benzaldehyde. Yellow solid. Yield=95%. MS: m/e=259.1 (M+).

Sources & evidence

ORD record: ord-9474082fc1d5402cade11d2754f5d944
Source dataset: uspto-grants-2004_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06762320B2

Reaction notes

Loading…