1-Iodopentane → HCID 14693034, compound

HRID 1885116Notes

Reaction equation

HRID 1885116 reaction equation
[C:1]([O:6][CH2:7][CH3:8])(=[O:5])[C@H:2]([CH3:4])[OH:3].I[CH2:10][CH2:11][CH2:12][CH2:13][CH3:14]>CCOCC>[CH2:10]([O:3][CH:2]([CH3:4])[C:1]([O:6][CH2:7][CH3:8])=[O:5])[CH2:11][CH2:12][CH2:13][CH3:14]

Participants

4

Reactant 2

HCID 123351-IodopentaneHCID 92831(L)-ethyl lactate

Product 1

HCID 14693034HCID 14693034, compoundYield 43.5%

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

98 g of ethyl L-lactate, 313 g of 1-iodopentane and 245 g of freshly prepared Ag2O were stirred at 60°-65° C. for 16 hours, and diluted with ether, followed by removal of insoluble matter by filtration. After distilling off the ether, the reaction liquid was distilled in vacuo to obtain 68 g of ethyl 2-pentyloxypropionate.

Workup

  1. customfollowed by removal of insoluble matter by filtration
  2. distillationAfter distilling off the ether
  3. customthe reaction liquid
  4. distillationwas distilled in vacuo

Sources & evidence

ORD record
ord-a421a0b008d14cd7935990647272d82c
Source dataset
uspto-grants-1992_09
Patent number
US05143643

Reaction notes

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