反应详情

(Compound 15) (12.5 g) was treated with butylamine (40 ml) in THF (75 ml) at RT for 4 h. The mixture evaporated and the residue extracted with OH- /ether. The ether phase washed with H2O and saturated NaCl-solution, dried (MgSO4) and evaporated giving 6.2 g of 3-butylamino-1-phenyl-1-propanol (compound 16). Identified by 1H NMR.

1. customThe mixture evaporated
2. extractionthe residue extracted with OH- /ether
3. washThe ether phase washed with H2O and saturated NaCl-solution
4. dry with materialdried (MgSO4)
5. customevaporated