m-Chloroperbenzoic acid → HCID 19879318, compound

HRID 1885574Notes

Reaction equation

HRID 1885574 reaction equation
ClC1C=CC=C(C(OO)=[O:9])C=1.[Cl:12][C:13]1[S:17][C:16]([CH:18]=[CH:19][CH2:20][OH:21])=[CH:15][CH:14]=1>ClCCl>[O:9]1[CH:18]([C:16]2[S:17][C:13]([Cl:12])=[CH:14][CH:15]=2)[CH:19]1[CH2:20][OH:21]

Participants

4

Reactant 2

HCID 70297m-Chloroperbenzoic acidHCID 53922212HCID 53922212, compound

Product 1

HCID 19879318HCID 19879318, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

0.75 g of m-chloroperbenzoic acid is added to a stirred solution of 0.6 g of 3-(5-chlorothiophen-2-yl)-prop-2-enol according to c) in 50 ml of dichloromethane. The solution is stirred at room temperature for 5 hours, washed with 10% sodium carbonate solution, dried over sodium sulfate and concentrated by evaporation. The residue is chromatographed on silica gel with ether and the title compound is obtained in the form of a light-yellow oil.

Workup

  1. washwashed with 10% sodium carbonate solution
  2. dry with materialdried over sodium sulfate
  3. concentrationconcentrated by evaporation
  4. customThe residue is chromatographed on silica gel with ether

Sources & evidence

ORD record
ord-8b94f37a06b24170bc8c24ffbf895820
Source dataset
uspto-grants-1992_09
Patent number
US05145868

Reaction notes

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