Dichloromethane → 9-Hydroxy-5-methoxy-7-(4-trifluoromethyl-benzyl)-6,7-dihydro-pyrrolo[3,4-g]quinolin-8-one
Reaction equation
[CH2:38]([SiH:39]([CH2:40][CH3:41])[CH2:42][CH3:43])[CH3:44].[CH3:1][O:2][c:3]1[c:4]2[cH:5][cH:6][cH:7][n:8][c:9]2[c:10]([O:28][CH2:29][c:30]2[cH:31][cH:32][c:33]([O:34][CH3:35])[cH:36][cH:37]2)[c:11]2[c:12]1[CH2:13][N:14]([CH2:17][c:18]1[cH:19][cH:20][c:21]([C:24]([F:25])([F:26])[F:27])[cH:22][cH:23]1)[C:15]2=[O:16].[Cl:52][CH2:53][Cl:54].[OH:45][C:46]([C:47]([F:48])([F:49])[F:50])=[O:51]>>[CH3:1][O:2][c:3]1[c:4]2[cH:5][cH:6][cH:7][n:8][c:9]2[c:10]([OH:28])[c:11]2[c:12]1[CH2:13][N:14]([CH2:17][c:18]1[cH:19][cH:20][c:21]([C:24]([F:25])([F:26])[F:27])[cH:22][cH:23]1)[C:15]2=[O:16]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-310b1953efb64f738e6af72c34ad46e5
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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