Isopropanol → HCID 86744106, compound

HRID 1885727Notes

Reaction equation

HRID 1885727 reaction equation
[CH3:1][N:2]([CH3:11])[CH2:3][CH2:4][CH2:5][NH:6][C:7]([NH:9][NH2:10])=[S:8].[N+:12]([C:15]1[O:19][C:18]([CH:20]=O)=[CH:17][CH:16]=1)([O-:14])=[O:13].[CH3:22][S:23]([OH:26])(=[O:25])=[O:24].C(O)(C)C>C(O)C>[CH3:22][S:23]([OH:26])(=[O:25])=[O:24].[N+:12]([C:15]1[O:19][C:18]([CH:20]=[N:10][NH:9][C:7](=[S:8])[NH:6][CH2:5][CH2:4][CH2:3][N:2]([CH3:1])[CH3:11])=[CH:17][CH:16]=1)([O-:14])=[O:13]

Participants

6

Reactant 4

HCID 3776IsopropanolHCID 6395Methanesulfonic AcidHCID 127745-NitrofurfuralHCID 10012455HCID 10012455, compound

Product 1

HCID 86744106HCID 86744106, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

N-(3-dimethylaminopropyl)hydrazinecarbothioamide (0.12 g) was reacted with 5-nitro-2-furaldehyde (0.15 g) in 5 ml ethanol at reflux for 15 minutes. The mixture was cooled and treated with methanesulfonic acid (0.055 ml) and isopropanol and stored at 4° C. to give 0.15 g of the title compound as orange needles, mp 184°-187° C.

Workup

  1. temperatureat reflux for 15 minutes
  2. temperatureThe mixture was cooled
  3. customstored at 4° C.

Sources & evidence

ORD record
ord-73c2d7cef6a74738887ef340e484baf7
Source dataset
uspto-grants-1992_09
Patent number
US05145975

Reaction notes

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