Trifluoroacetic acid → 2-(12-Phthalimido dodecyl)propane dioic acid

HRID 1886746Notes

Reaction equation

HRID 1886746 reaction equation
C([O:5][C:6](=[O:38])[CH:7]([CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][N:27]1[C:31](=[O:32])[C:30]2=[CH:33][CH:34]=[CH:35][CH:36]=[C:29]2[C:28]1=[O:37])[C:8]([O:10]C(C)(C)C)=[O:9])(C)(C)C.FC(F)(F)C(O)=O>ClCCl>[C:28]1(=[O:37])[N:27]([CH2:26][CH2:25][CH2:24][CH2:23][CH2:22][CH2:21][CH2:20][CH2:19][CH2:18][CH2:17][CH2:16][CH2:15][CH:7]([C:6]([OH:38])=[O:5])[C:8]([OH:10])=[O:9])[C:31](=[O:32])[C:30]2=[CH:33][CH:34]=[CH:35][CH:36]=[C:29]12

Participants

4

Reactant 2

HCID 6422Trifluoroacetic acidHCID 866489122-(12-Phthalimido dodecyl)propane dioic acid di-tert-butyl ester

Product 1

HCID 866489112-(12-Phthalimido dodecyl)propane dioic acidYield 100%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Following general procedure D, 16.0 mmol (8.45 g) of 5c and 160 mmol (11.9 mL) of trifluoroacetic acid were reacted in 12 mL of dichloromethane at room temperature and the mixture was processed. Yield 100%.

Sources & evidence

ORD record
ord-2c5e79c602a84d9fa0caec80d5c30337
Source dataset
uspto-grants-2013_08
Patent number
US08501199B2

Reaction notes

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