Hydrazine hydrate (1:1) → 3-(2,2-Dimethylpropyl)-5,6,7,8-tetrahydro-5,8-ethanocinnoline

HRID 1888884Notes

Reaction equation

HRID 1888884 reaction equation
[CH:1]12[CH2:8][CH2:7][CH:4]([CH2:5][CH2:6]1)[C:3](=O)[C:2]2=O.COP([CH2:17][C:18](=O)[CH2:19][C:20]([CH3:23])([CH3:22])[CH3:21])(=O)OC.O.[NH2:26][NH2:27]>>[CH3:21][C:20]([CH3:23])([CH3:22])[CH2:19][C:18]1[N:26]=[N:27][C:2]2[CH:1]3[CH2:8][CH2:7][CH:4]([C:3]=2[CH:17]=1)[CH2:5][CH2:6]3

Participants

4

Reactant 3

HCID 24654Hydrazine hydrate (1:1)HCID 548936Bicyclo[2.2.2]octane-2,3-dioneHCID 25112585(4,4-Dimethyl-2-oxo-pentyl)-phosphonic acid dimethyl ester

Product 1

HCID 461753283-(2,2-Dimethylpropyl)-5,6,7,8-tetrahydro-5,8-ethanocinnoline

Procedure

White solid MS (ESI): 231.1 (MH+). Prepared from bicyclo[2.2.2]octane-2,3-dione, (4,4-dimethyl-2-oxo-pentyl)-phosphonic acid dimethyl ester, hydrazine monohydrate.

Sources & evidence

ORD record
ord-ed171f453f6b406da2ed572e56693259
Source dataset
uspto-grants-2013_08
Patent number
US08501940B2

Reaction notes

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