Hydrochloric Acid → 8-fluoro-4-[3-(3-methoxypropyl)piperazin-1-yl]-2-methyl-10H-thieno[2,3-b][1,5]benzodiazepine
Reaction equation
[CH3:19][O:20][CH2:21][CH2:22][CH2:23][CH:24]1[NH:25][CH2:26][CH2:27][NH:28][CH2:29]1.[CH3:39][c:40]1[cH:41][cH:42][cH:43][cH:44][cH:45]1.[CH3:46][S:47]([CH3:48])=[O:49].[CH:30]([N:31]([CH:32]([CH3:33])[CH3:34])[CH2:35][CH3:36])([CH3:37])[CH3:38].[ClH:1].[F:2][c:3]1[cH:4][cH:5][c:6]2[c:7]([cH:18]1)[NH:8][c:9]1[s:10][c:11]([CH3:17])[cH:12][c:13]1[C:14]([NH2:16])=[N:15]2>>[F:2][c:3]1[cH:4][cH:5][c:6]2[c:7]([cH:18]1)[NH:8][c:9]1[s:10][c:11]([CH3:17])[cH:12][c:13]1[C:14]([N:16]1[CH2:27][CH2:26][NH:25][CH:24]([CH2:23][CH2:22][CH2:21][O:20][CH3:19])[CH2:29]1)=[N:15]2Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-4f5b6f029a6645d681554bc9a6b121b7
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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