反应详情

(3-Nitrophenyl)methanesulfonyl chloride (0.6 g, 2.55 mmol) was dissolved in acetonitrile (10 mL), then to this solution was added propylamine (0.247 mL, 3 mmol) and triethylamine (1 mL). The reaction mixture was allowed to vigorously stir for 3 h at room temperature, then the diluted with cold water (30 ml), leading to a precipitate formation. The precipitate was filtered off, washed with water (2×10 mL) and dried under reduced pressure. Yield of (3-nitrophenyl)-N-propylmethanesulfonamide 0.63 g (95%).

1. filtrationThe precipitate was filtered off
2. washwashed with water (2×10 mL)
3. customdried under reduced pressure