HRID1893313

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID15908

1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimide

C8H17N3

HCID1516507

1-Boc-3-(amino)azetidine

C8H16N2O2

结构：O=C(O)CNC(=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1

HCID2797421

Glycine, N-[3,5-bis(trifluoromethyl)benzoyl]-

C11H7F6NO3

PRODUCTS

生成物

结构：CC(C)(C)OC(=O)N1CC(NC(=O)CNC(=O)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)C1

HCID59361639

未命名化合物

PROCEDURE

实验过程

The title compounds were prepared as white solids from the EDCI coupling between 3-amino-azetidine-1-carboxylic acid tert-butyl ester and (3,5-bistrifluoromethyl-benzoylamino)-acetic acid (analog synthesis by following the procedure on Organic Synthesis XII, 40-2, 1932) using the procedure described in Step F of Example 1.

WORKUP

后处理

customanalog synthesis