Bromide ion → 2-[8-(1-Ethyl-propyl)-2,6-dimethyl-imidazo[1,2-b]pyridazin-3-yl]-5-(6-methyl-pyridin-2-yl)-thiophene-3-carbonitrile

HRID 189479Notes

Reaction equation

HRID 189479 reaction equation
[Br-:25].[Br:1][c:2]1[cH:3][c:4]([C:23]#[N:24])[c:5](-[c:7]2[c:8]([CH3:22])[n:9][c:10]3[n:11]2[n:12][c:13]([CH3:21])[cH:14][c:15]3[CH:16]([CH2:17][CH3:18])[CH2:19][CH3:20])[s:6]1.[CH2:34]1[O:35][CH2:36][CH2:37][CH2:38]1.[CH3:26][c:27]1[cH:28][cH:29][cH:30][c:31]([Zn+:33])[n:32]1.[CH3:39][CH2:40][O:41][C:42]([CH3:43])=[O:44]>>[c:2]1(-[c:31]2[cH:30][cH:29][cH:28][c:27]([CH3:26])[n:32]2)[cH:3][c:4]([C:23]#[N:24])[c:5](-[c:7]2[c:8]([CH3:22])[n:9][c:10]3[n:11]2[n:12][c:13]([CH3:21])[cH:14][c:15]3[CH:16]([CH2:17][CH3:18])[CH2:19][CH3:20])[s:6]1

Participants

6

Reactant 5

HCID 259Bromide ionHCID 8028TetrahydrofuranHCID 8857Ethyl AcetateHCID 57932902HCID 57932902, compoundHCID 178426001HCID 178426001, compound

Product 1

HCID 579330662-[8-(1-Ethyl-propyl)-2,6-dimethyl-imidazo[1,2-b]pyridazin-3-yl]-5-(6-methyl-pyridin-2-yl)-thiophene-3-carbonitrile

Sources & evidence

ORD record
ord-eae23a6482a44fa2a6b8052eb6e43e2b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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