反应详情

The title compound was prepared following the procedure described for the compound of Example 42, but using Compound 248a instead of the Compound of Example 3 and 2-bromobenzonitrile instead of bromobenzene. The crude was purified by preparative RP LC-MS chromatography, using MS-C18 XTerra column 30×50 mm eluting with ammonium bicarbonate 20 mM pH 8 buffer-acetonitrile gradient, affording the title product as a brown oil.

1. customThe title compound was prepared
2. customThe crude was purified by preparative RP LC-MS chromatography
3. washeluting with ammonium bicarbonate 20 mM pH 8 buffer-acetonitrile gradient