反应详情

189 mg (0.52 mmol) of (2-(2-(6-(2-fluorophenyl)pyridin-3-yloxy)ethyl)isoindole-1,3-dione and 236 mg (4.72 mmol) of hydrazine hydrate (24%) were stirred in 10 ml of ethanol under reflux for 7 h. After cooling the residue was filtered, washed and dried. Yield: 165 mg.

1. temperatureunder reflux for 7 h
2. temperatureAfter cooling the residue
3. filtrationwas filtered
4. washwashed
5. customdried