Thiophosgene → HCID 18464324, compound

HRID 1898305Notes

Reaction equation

HRID 1898305 reaction equation
[C:1]([C:5]1[CH:11]=[CH:10][CH:9]=[CH:8][C:6]=1[NH2:7])([CH3:4])([CH3:3])[CH3:2].[C:12](Cl)(Cl)=[S:13].C(N(C(C)C)C(C)C)C>>[C:1]([C:5]1[CH:11]=[CH:10][CH:9]=[CH:8][C:6]=1[N:7]=[C:12]=[S:13])([CH3:4])([CH3:2])[CH3:3]

Participants

4

Reactant 3

HCID 10040ThiophosgeneHCID 805742-tert-ButylanilineHCID 81531Diisopropylethylamine

Product 1

HCID 18464324HCID 18464324, compoundYield 47.5%

Procedure

The title compound was prepared following the procedure described for intermediate-2 using 2-tert-butylaniline (5.0 g, 0.033 mol), thiophosgene (3.80 g, 0.033 mol) and N-ethyl di-isopropyl amine (8.5 g, 0.066 mol) to afford 3.0 g of the desired product.

Workup

  1. customThe title compound was prepared

Sources & evidence

ORD record
ord-4e1a172fb4e242a6abb58dae9e18c706
Source dataset
uspto-grants-2013_08
Patent number
US08519149B2

Reaction notes

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