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HRID1898415

反应详情

EQUATION

反应方程式

HRID 1898415 的结构方程式

REACTANTS

反应物

2
结构：Cl
HCID313

Hydrochloric Acid

ClH

结构：Cc1cccc(Cl)c1Nc1nc2cc(C(=O)Nc3cc(C(F)(F)F)ccc3F)c3c(c2[nH]1)CC(C)(C)O3
HCID178425058

未命名化合物

PRODUCTS

生成物

1
结构：Cc1cccc(Cl)c1Nc1nc2cc(C(=O)Nc3cc(C(F)(F)F)ccc3F)c3c(c2[nH]1)CC(C)(C)O3.Cl
HCID178425059

未命名化合物

收率 187.2%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：C1CCOC1
溶剂HCID8028

Tetrahydrofuran

C4H8O

PROCEDURE

实验过程

The title compound was prepared following the procedure described for Example-146 using 2-[(2-chloro-6-methylphenyl)amino]-N-[2-fluoro-5-(trifluoromethyl)phenyl]-7,7-dimethyl-7,8-dihydro-1H-furo[3,2-e]benzimidazole-5-carboxamide (Example-110, 0.100 g), THF (10 mL) and solution of HCl in DEE to afford 0.100 g of the desired product.

WORKUP

后处理

  1. customThe title compound was prepared