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HRID1898689

反应详情

EQUATION

反应方程式

HRID 1898689 的结构方程式

REACTANTS

反应物

3
结构：CC(C)CN
HCID6558

Isobutylamine

C4H11N

结构：Cc1c(C)c2c(c(C)c1O)CCC(C)(C(=O)O)O2
HCID40634

Trolox

C14H18O4

结构：O=C(n1ccnc1)n1ccnc1
HCID68263

1,1'-Carbonylbis(1H-imidazole)

C7H6N4O

PRODUCTS

生成物

1
结构：Cc1c(C)c2c(c(C)c1O)CCC(C)(C(=O)NCC(C)C)O2
HCID67263059

未命名化合物

收率 75%

PROCEDURE

实验过程

Following the amide coupling procedure described in protocol A, 510 mg 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid (2.04 mmol), 357 mg CDI (2.20 mmol) and 161 mg isobutylamine (2.2 mmol) produced 467 mg of 6-hydroxy-N-isobutyl-2,5,7,8-tetramethylchroman-2-carboxamide as an off-white solid.