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HRID1898691

反应详情

EQUATION

反应方程式

HRID 1898691 的结构方程式

REACTANTS

反应物

3
结构：Cc1c(C)c2c(c(C)c1O)CCC(C)(C(=O)O)O2
HCID40634

Trolox

C14H18O4

结构：O=C(n1ccnc1)n1ccnc1
HCID68263

1,1'-Carbonylbis(1H-imidazole)

C7H6N4O

结构：OC1CCNCC1
HCID79341

Piperidin-4-ol

C5H11NO

PRODUCTS

生成物

1
结构：Cc1c(C)c2c(c(C)c1O)CCC(C)(C(=O)N1CCC(O)CC1)O2
HCID67263066

未命名化合物

收率 33.3%

PROCEDURE

实验过程

Following the amide coupling procedure described in protocol A, 500 mg 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid (2.0 mmol), 370 mg CDI (2.28 mmol) and 222 mg 4-hydroxypiperidine (2.20 mmol) produced 222 mg of a (6-hydroxy-2,5,7,8-tetramethylchroman-2-yl)(4-hydroxypiperidin-1-yl)methanone as a white foam.