Hydrochloric Acid → 4-[1-(1-ethylbut-3-yn-1-yl)-1H-pyrazol-4-yl]-7-[2-(trimethylsilyl)ethoxy]methyl-7H-pyrrolo[2,3-d]pyrimidine
Reaction equation
[Br:1][C:2](=[CH:3][CH2:4][CH:5]([CH2:6][CH3:7])[n:8]1[n:9][cH:10][c:11](-[c:13]2[c:14]3[c:15]([n:16][cH:17][n:18]2)[n:19]([CH2:22][O:23][CH2:24][CH2:25][Si:26]([CH3:27])([CH3:28])[CH3:29])[cH:20][cH:21]3)[cH:12]1)[Br:30].[CH2:31]1[O:32][CH2:33][CH2:34][CH2:35]1.[CH2:36]([Li:37])[CH2:38][CH2:39][CH3:40].[CH3:43][CH2:44][CH2:45][CH2:46][CH2:47][CH3:48].[ClH:42].[OH2:41]>>[CH:2]#[C:3][CH2:4][CH:5]([CH2:6][CH3:7])[n:8]1[n:9][cH:10][c:11](-[c:13]2[c:14]3[c:15]([n:16][cH:17][n:18]2)[n:19]([CH2:22][O:23][CH2:24][CH2:25][Si:26]([CH3:27])([CH3:28])[CH3:29])[cH:20][cH:21]3)[cH:12]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-6909c7a32de9454b9730baaaf6a37d3b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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