Dichloromethane → N-(7-{[1-(morpholine-4-carbonyl)-piperidin-4-ylmethyl]-propyl-amino}-5,6,7,8-tetrahydro-naphthalen-2-yl)-isobutyramide

HRID 189998Notes

Reaction equation

HRID 189998 reaction equation
[C:31]([CH:32]([CH3:33])[CH3:34])(=[O:35])[Cl:36].[CH:40]([N:41]([CH2:42][CH3:43])[CH:44]([CH3:45])[CH3:46])([CH3:47])[CH3:48].[Cl:37][CH2:38][Cl:39].[NH2:1][c:2]1[cH:3][cH:4][c:5]2[c:10]([cH:11]1)[CH2:9][CH:8]([N:12]([CH2:13][CH2:14][CH3:15])[CH2:16][CH:17]1[CH2:18][CH2:19][N:20]([C:23](=[O:24])[N:25]3[CH2:26][CH2:27][O:28][CH2:29][CH2:30]3)[CH2:21][CH2:22]1)[CH2:7][CH2:6]2>>[NH:1]([c:2]1[cH:3][cH:4][c:5]2[c:10]([cH:11]1)[CH2:9][CH:8]([N:12]([CH2:13][CH2:14][CH3:15])[CH2:16][CH:17]1[CH2:18][CH2:19][N:20]([C:23](=[O:24])[N:25]3[CH2:26][CH2:27][O:28][CH2:29][CH2:30]3)[CH2:21][CH2:22]1)[CH2:7][CH2:6]2)[C:31]([CH:32]([CH3:33])[CH3:34])=[O:35]

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 62325Isobutyryl chlorideHCID 81531DiisopropylethylamineHCID 22560664(4-{[(7-Amino-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amino]-methyl)-piperidin-1-yl)-morpholin-4-yl-methanone

Product 1

HCID 21362785N-(7-{[1-(morpholine-4-carbonyl)-piperidin-4-ylmethyl]-propyl-amino}-5,6,7,8-tetrahydro-naphthalen-2-yl)-isobutyramide

Sources & evidence

ORD record
ord-c97a07a172bc46e1b5df2af85f714bb9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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