Sodium Azide → HCID 23369740, compound

HRID 1900825Notes

Reaction equation

HRID 1900825 reaction equation
Br[CH2:2][CH:3]1[O:18][C:6]2=[C:7]3[C:12](=[C:13]([CH3:15])[CH:14]=[C:5]2[CH:4]1[CH2:19][CH3:20])[NH:11][C:10](=[O:16])[C:9]([CH3:17])=[CH:8]3.[N-:21]=[N+:22]=[N-:23].[Na+]>CN(C)C=O>[N:21]([CH2:2][CH:3]1[O:18][C:6]2=[C:7]3[C:12](=[C:13]([CH3:15])[CH:14]=[C:5]2[CH:4]1[CH2:19][CH3:20])[NH:11][C:10](=[O:16])[C:9]([CH3:17])=[CH:8]3)=[N+:22]=[N-:23]

Participants

4

Reactant 2

HCID 33557Sodium AzideHCID 23369609HCID 23369609, compound

Product 1

HCID 23369740HCID 23369740, compoundYield 57.5%

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

The title compound was prepared in a manner similar to that described in Example 274 using the compound obtained in Example 292 (46 mg, 0.14 mmol), sodium azide (53 mg, 0.82 mmol) and dimethylformamide (1.0 ml). 24 mg of the title compound was obtained as a pale yellow solid (58.8%).

Workup

  1. customThe title compound was prepared in a manner similar to

Sources & evidence

ORD record
ord-6efdf1e7ad9e49ce8bf07c350259088d
Source dataset
uspto-grants-1996_11
Patent number
US05576324

Reaction notes

Loading…