Dimethylformamide → (4-fluorophenyl)(4-(5-methyl-1H-pyrazol-3-ylamino)quinazolin-2-yl)methanone

HRID 190094Notes

Reaction equation

[CH3:30][c:31]1[cH:32][c:33]([NH2:36])[n:34][nH:35]1.[CH:21]([N:22]([CH2:23][CH3:24])[CH:25]([CH3:26])[CH3:27])([CH3:28])[CH3:29].[Cl:1][c:2]1[n:3][c:4]([C:12](=[O:13])[c:14]2[cH:15][cH:16][c:17]([F:20])[cH:18][cH:19]2)[n:5][c:6]2[cH:7][cH:8][cH:9][cH:10][c:11]12.[O:37]=[CH:38][N:39]([CH3:40])[CH3:41]>>[c:2]1([NH:36][c:33]2[cH:32][c:31]([CH3:30])[nH:35][n:34]2)[n:3][c:4]([C:12](=[O:13])[c:14]2[cH:15][cH:16][c:17]([F:20])[cH:18][cH:19]2)[n:5][c:6]2[cH:7][cH:8][cH:9][cH:10][c:11]12

Participants

Reactant 4

HCID 6228Dimethylformamide

HCID 81531Diisopropylethylamine

HCID 931461H-Pyrazol-3-amine, 5-methyl-

HCID 86649048(4-Chloroquinazolin-2-yl)(4-fluorophenyl)methanone

Product 1

HCID 46892243(4-fluorophenyl)(4-(5-methyl-1H-pyrazol-3-ylamino)quinazolin-2-yl)methanone

Sources & evidence

ORD record: ord-171aea1952d849e49669d35f78e38cb4
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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