HRID1901080

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID392870

1-tert-Butyl 4-methyl piperidine-1,4-dicarboxylate

C12H21NO4

HCID2724682

2-Propanamine, N-(1-methylethyl)-, lithium salt

C6H14LiN

PRODUCTS

生成物

结构：COC(=O)C1(Cc2ccccc2C)CCN(C(=O)OC(C)(C)C)CC1

HCID53775443

1-(1,1-Dimethylethyl) 4-methyl 4-[(2-methylphenyl)methyl]-1,4-piperidinedicarboxylate

C20H29NO4

PROCEDURE

实验过程

N-t-butoxycarbonyl isonipecotic acid methyl ester was transformed utilizing the alkylation procedure as described in Example 1, Step 3 substituting lithium diisopropylamide as the base to afford the product as a yellow syrup.