反应详情

To a solution of 2-(tert-butyldiphenylsiloxy)methyl-6-phenylpyridine (1.2 g) in THF (20 mL) was added Bu4NF (3.3 mL of a 1M solution in THF). After 1 h, NH4OAc buffer was added and the mixture extracted with EtOAc. The organics were dried (MgSO4), concentrated and chromatographed (silica gel; hexane/EtOAc acetate (3:2)) to provide the title compound as a solid.

1. extractionthe mixture extracted with EtOAc
2. dry with materialThe organics were dried (MgSO4)
3. concentrationconcentrated
4. customchromatographed (silica gel; hexane/EtOAc acetate (3:2))