HCID 178490738, compound → HCID 178490736, compound

HRID 1902864Notes

Reaction equation

HRID 1902864 reaction equation
C([O:8][N:9]1[CH2:13][CH2:12][NH:11][C:10]1=[N:14][C:15]1[CH:20]=[C:19]([O:21][CH3:22])[CH:18]=[CH:17][C:16]=1[Cl:23])C1C=CC=CC=1>C(O)C.Cl.[Pd]>[ClH:23].[Cl:23][C:16]1[CH:17]=[CH:18][C:19]([O:21][CH3:22])=[CH:20][C:15]=1[N:14]=[C:10]1[NH:11][CH2:12][CH2:13][N:9]1[OH:8]

Participants

5

Reactant 1

HCID 178490738HCID 178490738, compound

Product 1

HCID 178490736HCID 178490736, compound

Reagents, catalysts & solvents 3

HCID 23938PalladiumCatalystHCID 313Hydrochloric AcidSolventHCID 702EthanolSolvent

Procedure

A solution of 1.84 g of 1-(benzyloxy)-2-[(2-chloro-5-methoxyphenyl)imino]imidazolidine in 10 ml of ethanol and 0.65 ml of 25 percent hydrochloric acid is hydrogenated over palladium/carbon. The catalyst is subsequently removed by filtration and the solution obtained is evaporated in vacuo. There is obtained 2-[(2-chloro-5-methoxyphenyl)imino]-1-hydroxyimidazolidine hydrochloride of melting point 182°-184° (acetone).

Workup

  1. customThe catalyst is subsequently removed by filtration
  2. customthe solution obtained
  3. customis evaporated in vacuo

Sources & evidence

ORD record
ord-e9dcf08f8d8c468d983161204598c6ee
Source dataset
uspto-grants-1982_12
Patent number
US04366160

Reaction notes

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