反应详情

A solution of 3.1 g of potassium hydroxide in 40 ml of methanol is added to a mixture of 150 ml of dimethylformamide, 6.9 g of beta-carboline-3-carboxaldehyde and 3.1 g of hydroxylamino-hydrochloride. The reaction mixture is allowed to stand at room temperature overnight. After evaporation, 50 ml of water is added. The reaction product is filtered off. 6.9 g of the air-dried product is heated in the steam bath together with 35 ml of 2 propanol and, after cooling, is filtered off. 5 g of beta-carboline-3-carboxaldehyde-oxime with a melting point of 229°-231° C. is obtained.

1. customAfter evaporation, 50 ml of water
2. additionis added
3. filtrationThe reaction product is filtered off
4. temperature6.9 g of the air-dried product is heated in the steam bath together with 35 ml of 2 propanol
5. temperatureafter cooling
6. filtrationis filtered off