反应详情

A solution of 0.5 g aminopyridin and 0.7 ml triethylamine with 5 ml acetone was added dropwise to a suspension of 1.5 g phenylcarbamoyl-benzoic acid sulfimide with 15 ml aceton, under stirring. The reaction mixture was stirred for 45 minutes at room temperature, then diluted with 100 ml water. The acetone was distilled off, the residue was cooled, and the precipitated solid product was filtered, washed with water and dried. 0.6 g 1-phenyl-3-(2-pyridyl)-urea was obtained with a melting point of 185°-186° C.

1. stirringThe reaction mixture was stirred for 45 minutes at room temperature
2. distillationThe acetone was distilled off
3. temperaturethe residue was cooled
4. filtrationthe precipitated solid product was filtered
5. washwashed with water
6. customdried