反应详情

温度

25 °C

To a solution of sodium methoxide (5.0 millimoles) in methanol (100 ml), freshly generated by the careful portionwise additions of sodium (1.15 g, 5.0 millimole) to methanol (100 ml.), is added 4,5-dichloro-m-benzenedisulfonamide (15.16 g, 5.0 millimole) with stirring at 25° C. The resulting mixture is stirred at 25° C. for 30 minutes to provide a colorless solution which is filtered. Evaporation of the clear, colorless filtrate at 40° C. in vacuo provides a solid residue which is dried in vacuo at 80° C. for 16 hours to provide analytically pure 4,5-dichloro-m-benzenedisulfonamide mono sodium salt as a colorless solid (14.0 g., 85%), m.p./252°-244° C.

1. stirringThe resulting mixture is stirred at 25° C. for 30 minutes
2. customto provide a colorless solution which
3. filtrationis filtered
4. customEvaporation of the clear, colorless filtrate at 40° C. in vacuo
5. customprovides a solid residue which
6. customis dried in vacuo at 80° C. for 16 hours