3,4,5,6-Tetrahydrophthalic anhydride → N-(3-Hydroxy-4-chlorophenyl)-3,4,5,6-tetrahydrophthalimide

HRID 1903893Notes

Reaction equation

HRID 1903893 reaction equation
[OH:1][C:2]1[CH:3]=[C:4]([CH:6]=[CH:7][C:8]=1[Cl:9])[NH2:5].[C:10]1(=O)[O:15][C:13](=[O:14])[C:12]2[CH2:16][CH2:17][CH2:18][CH2:19][C:11]1=2>C(O)(=O)C>[OH:1][C:2]1[CH:3]=[C:4]([N:5]2[C:13](=[O:14])[C:12]3[CH2:16][CH2:17][CH2:18][CH2:19][C:11]=3[C:10]2=[O:15])[CH:6]=[CH:7][C:8]=1[Cl:9]

Participants

4

Reactant 2

HCID 124753,4,5,6-Tetrahydrophthalic anhydrideHCID 806765-Amino-2-chlorophenol

Product 1

HCID 12769235N-(3-Hydroxy-4-chlorophenyl)-3,4,5,6-tetrahydrophthalimide

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

Employed 47.5 g of 3-hydroxy-4-chloroaniline (0.33 mol); 38.2 of 3,4,5,6-tetrahydrophthalic anhydride (0.25 mol) and 350 ml of glacial acetic acid.

Sources & evidence

ORD record
ord-409fc4fa12124257a8cc85edb33c9516
Source dataset
uspto-grants-1984_03
Patent number
US04439229

Reaction notes

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