Benzenesulfonyl chloride → HCID 178430934, compound

HRID 1904026Notes

Reaction equation

HRID 1904026 reaction equation
[C:1]([C:3]1[C:4](=[O:22])[N:5]([CH3:21])[C:6]([OH:20])=[C:7]([N:10]=[N:11][C:12]2[CH:17]=[CH:16][C:15]([CH2:18][OH:19])=[CH:14][CH:13]=2)[C:8]=1[CH3:9])#[N:2].[C:23]1([S:29](Cl)(=[O:31])=[O:30])[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1>N1C=CC=CC=1.CC(N(C)C)=O>[C:1]([C:3]1[C:4](=[O:22])[N:5]([CH3:21])[C:6]([OH:20])=[C:7]([N:10]=[N:11][C:12]2[CH:17]=[CH:16][C:15]([CH2:18][O:19][S:29]([C:23]3[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=3)(=[O:31])=[O:30])=[CH:14][CH:13]=2)[C:8]=1[CH3:9])#[N:2]

Participants

5

Reactant 2

HCID 7369Benzenesulfonyl chlorideHCID 178430933HCID 178430933, compound

Product 1

HCID 178430934HCID 178430934, compoundYield 49.3%

Reagents, catalysts & solvents 2

HCID 1049PyridineSolventHCID 31374DimethylacetamideSolvent

Procedure

14.9 g of Compound [2-a] was benzenesulfonylated in the same manner as described in Step 1-h using 12 g of benzenesulfonyl chloride in 50 ml of pyridine and 20 ml of dimethylacetamide to obtain 10.8 g of Compound [2-b].

Sources & evidence

ORD record
ord-754f4af5e7284516a5e30adfdcced668
Source dataset
uspto-grants-1984_03
Patent number
US04439513

Reaction notes

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