Bromobenzene → 5-(3-fluoro-4-(2-iodothieno[3,2-b]pyridin-7-yloxy)phenyl)-3-methyl-2-(phenylamino)pyrimidin-4(3H)-one
Reaction equation
[Br:44][c:45]1[cH:46][cH:47][cH:48][cH:49][cH:50]1.[CH3:35][N:36]([c:37]1[cH:38][cH:39][n:40][cH:41][cH:42]1)[CH3:43].[Cl:24][c:25]1[c:26]2[c:27]([n:28][cH:29][cH:30]1)[cH:31][c:32]([I:34])[s:33]2.[F:1][c:2]1[cH:3][c:4](-[c:9]2[c:10](=[O:23])[n:11]([CH3:22])[c:12]([NH:15][c:16]3[cH:17][cH:18][cH:19][cH:20][cH:21]3)[n:13][cH:14]2)[cH:5][cH:6][c:7]1[OH:8]>>[F:1][c:2]1[cH:3][c:4](-[c:9]2[c:10](=[O:23])[n:11]([CH3:22])[c:12]([NH:15][c:16]3[cH:17][cH:18][cH:19][cH:20][cH:21]3)[n:13][cH:14]2)[cH:5][cH:6][c:7]1[O:8][c:25]1[c:26]2[c:27]([n:28][cH:29][cH:30]1)[cH:31][c:32]([I:34])[s:33]2Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-808a30ba9b774aada478ebd85a640a1f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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