反应详情

4',5,7-Trihydroxy-2-bromomethylisoflavone (160 mg) was dissolved in 2 ml, N,N-dimethylformamide, 100 mg piperidine was added to the solution, and the mixture was stirred at room temperature for three hours. The solvent was distilled off under reduced pressure, the residue was purified by silca gel column chromatography (chlorofrom: methanol=96:4), and the solid thus obtained was recrystallized from ethanol, giving 150 mg of 4',5,7-trihydroxy-2-piperidinomethylisoflavone.

1. additionwas added to the solution
2. distillationThe solvent was distilled off under reduced pressure
3. customthe residue was purified by silca gel column chromatography (chlorofrom: methanol=96:4)
4. customthe solid thus obtained
5. customwas recrystallized from ethanol