Isoamyl Alcohol → HCID 14580252, compound

HRID 1905383Notes

Reaction equation

HRID 1905383 reaction equation
Cl.[N:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][C:9]([OH:11])=[O:10].[CH2:12](O)[CH2:13][CH:14]([CH3:16])[CH3:15].Cl.C(N=C=NCCCN(C)C)C>N1C=CC=CC=1.C(Cl)Cl>[CH2:12]([O:10][C:9](=[O:11])[CH2:8][C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][N:2]=1)[CH2:13][CH:14]([CH3:16])[CH3:15]

Participants

6

Reactant 3

HCID 31260Isoamyl AlcoholHCID 853172-Pyridineacetic acid, hydrochloride (1:1)HCID 27239391,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochloride

Product 1

HCID 14580252HCID 14580252, compound

Reagents, catalysts & solvents 2

HCID 1049PyridineSolventHCID 6344DichloromethaneSolvent

Procedure

A mixture of 2-pyridylacetic acid hydrochloride 10.00 g (57.60 mmol), iso-amyl alcohol 6.09 g (69.12 mmol) and 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride 14.35 g (74.88 mmol) in 20 ml of pyridine and 80 ml of methylene chloride was stirred at room temperature for 2 hr.

Sources & evidence

ORD record
ord-66b816e485f14bd7a565cd55e491db46
Source dataset
uspto-grants-1989_06
Patent number
US04843083

Reaction notes

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