反应详情

The same operation as in Example 1, (1-c) was carried out by using 6-(4-aminophenyl)-5-methyl-4,5-dihydro-3(2H)-pyridazinone (2.03 g), 2-butoxycarbonylamino)propanal (2.09 g), acetic acid (0.6 g) and sodium cyanoborohydride (0.33 g), to obtain 6-[4-(2-t-butoxycarbonylaminopropylamino)phenyl]-5-methyl-4,5-dihydro-3(2H)-pyridazinone (2.89 g).