Potassium Carbonate → HCID 14303266, compound

HRID 1905433Notes

Reaction equation

HRID 1905433 reaction equation
Cl[CH:2]1[CH2:7][CH:6]([CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH3:15])[O:5][C:3]1=[O:4].C(=O)([O-])[O-:17].[K+].[K+]>Cl>[OH:17][CH:2]1[CH2:7][CH:6]([CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH3:15])[O:5][C:3]1=[O:4]

Participants

4

Reactant 2

HCID 11430Potassium CarbonateHCID 3017732HCID 3017732, compound

Product 1

HCID 14303266HCID 14303266, compoundYield 78%

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

In a 50 ml flask with a cooling column, 3.5 g (15 mmol) of α-chloro-γ-octyl-γ-butyrolactone and 20 ml of 2N aqueous potassium carbonate were kept at 80° C. for 40 hours under stirring. The reaction mixture was cooled to room temperature and poured into 10 ml of 12N hydrochloric acid. The reaction product was extracted with ether and the ether extract was dried over anhydrous sodium carbonate. The ether was removed and the residue was distilled under reduced pressure to give α-hydroxy-γ-octyl-γ-butyrolactone (Yield 78%)

Workup

  1. extractionThe reaction product was extracted with ether
  2. extractionthe ether extract
  3. dry with materialwas dried over anhydrous sodium carbonate
  4. customThe ether was removed
  5. distillationthe residue was distilled under reduced pressure

Sources & evidence

ORD record
ord-caab51023e4e44608a4833b0ccb11272
Source dataset
uspto-grants-1989_06
Patent number
US04843093

Reaction notes

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