HCID 12930698, compound → HCID 13187941, compound

HRID 1905759Notes

Reaction equation

HRID 1905759 reaction equation
[Cl:1][C:2]1([Cl:13])[CH:7]2[CH2:8][CH:4]([CH:5]=[CH:6]2)[C:3]1([C:11]#[N:12])[C:9]#[N:10].[H][H]>C(OCC)(=O)C.[Pt]>[Cl:1][C:2]1([Cl:13])[CH:7]2[CH2:8][CH:4]([CH2:5][CH2:6]2)[C:3]1([C:11]#[N:12])[C:9]#[N:10]

Participants

5

Reactant 2

HCID 12930698HCID 12930698, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 13187941HCID 13187941, compoundYield 99.6%

Reagents, catalysts & solvents 2

HCID 23939PlatinumCatalystHCID 8857Ethyl AcetateSolvent

Conditions

Temperature
40 °C

Procedure

30 g (0.14 mol) of the (IV) prepared in Example 1 are dissolved in 170 ml of ethyl acetate, the solution is introduced into an autoclave, and 2 g of 1% strength platinum on carbon are added. The mixture is warmed to 40° C., and hydrogen is forced in until a pressure of 10 bar is reached. After approx. 2 hours, the reaction is complete. The catalyst is filtered off and the solvent is evaporated. 30 g (99%) of 3,3-dichlorobicyclo[2,2,1]heptane-2,2-dicarbonitrile, m.p. 148° C., are obtained.

Workup

  1. additionare added
  2. filtrationThe catalyst is filtered off
  3. customthe solvent is evaporated

Sources & evidence

ORD record
ord-50e20b6b175c4d5e95b5a12686859924
Source dataset
uspto-grants-1987_03
Patent number
US04647581

Reaction notes

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