Pyridine → HCID 53778288, compound

HRID 1905828Notes

Reaction equation

HRID 1905828 reaction equation
[CH3:1][CH:2]([O:5][C:6]1[CH:11]=[CH:10][C:9]([CH2:12][CH2:13][C:14](=O)[CH3:15])=[CH:8][CH:7]=1)[CH2:3][CH3:4].N1C=CC=CC=1.Cl.[CH2:24]([O:26][NH2:27])[CH3:25]>O1CCCC1>[CH2:24]([O:26][N:27]=[C:14]([CH2:13][CH2:12][C:9]1[CH:10]=[CH:11][C:6]([O:5][CH:2]([CH3:1])[CH2:3][CH3:4])=[CH:7][CH:8]=1)[CH3:15])[CH3:25]

Participants

5

Reactant 3

HCID 1049PyridineHCID 76850O-ethylhydroxylamine hydrochlorideHCID 20206284HCID 20206284, compound

Product 1

HCID 53778288HCID 53778288, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

Following the procedure of Example 1, 4-[4-(1-methylpropoxy)phenyl]-2-butanone (4.41 g, 20.0 mmol) and pyridine (3 ml) in 45 ml of tetrahydrofuran are reacted with ethoxyamine hydrochloride (4.41 g, 45.2 mmol) to give 4-[4-(1methylpropoxy)phenyl]-2-butanone O-ethyloxime, as a mixture of syn and anti stereo isomers. MS m/e 263 (M ).

Sources & evidence

ORD record
ord-2d3c3248b2c6452eb5efbe54b0209778
Source dataset
uspto-grants-1987_03
Patent number
US04647698

Reaction notes

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