Sodium Bicarbonate → HCID 13608180, compound

HRID 1905873Notes

Reaction equation

HRID 1905873 reaction equation
Cl.[CH2:2]1[O:10][C:9]2[CH:8]=[CH:7][C:6]([C:11]3[N:16]([CH2:17][CH3:18])[C:15](=[O:19])[N:14]([CH3:20])[C:13](=[N:21][C:22]4[C:27]([CH3:28])=[CH:26][C:25]([CH3:29])=[CH:24][C:23]=4[CH3:30])[CH:12]=3)=[CH:5][C:4]=2[O:3]1.C(=O)(O)[O-].[Na+]>O>[CH2:2]1[O:10][C:9]2[CH:8]=[CH:7][C:6]([C:11]3[N:16]([CH2:17][CH3:18])[C:15](=[O:19])[N:14]([CH3:20])[C:13](=[N:21][C:22]4[C:27]([CH3:28])=[CH:26][C:25]([CH3:29])=[CH:24][C:23]=4[CH3:30])[CH:12]=3)=[CH:5][C:4]=2[O:3]1

Participants

4

Reactant 2

HCID 516892Sodium BicarbonateHCID 20213351HCID 20213351, compound

Product 1

HCID 13608180HCID 13608180, compoundYield 93.7%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

To a solution of 3,4-dihydro-6-(3,4-methylenedioxyphenyl)-1-ethyl-3-methyl-4-(2,4,6-trimethylphenylimino)-2(1H)-pyrimidinone hydrochloride (70 mg) in water (10 ml) was neutralized with an aqueous solution of sodium bicarbonate. The resulting precipitates were collected by filtration to give 3,4-dihydro-6-(3,4-methylenedioxyphenyl)-1-ethyl-3-methyl-4-(2,4,6-trimethylphenylimino)-2(1H)-pyrimidinone (60 mg).

Workup

  1. customThe resulting precipitates
  2. filtrationwere collected by filtration

Sources & evidence

ORD record
ord-6dd07e88597348a7b89b911ba750606a
Source dataset
uspto-grants-1987_03
Patent number
US04649142

Reaction notes

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