Hydrochloric Acid → 4-Amino-3-hydroxy-6-methyl-1-phenylheptane hydrochloride

HRID 1906363Notes

Reaction equation

HRID 1906363 reaction equation
C(OC([NH:8][CH:9]([CH2:20][CH:21]([CH3:23])[CH3:22])[CH:10]([OH:19])[CH2:11][CH2:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)=O)(C)(C)C.[ClH:24]>CO>[ClH:24].[NH2:8][CH:9]([CH2:20][CH:21]([CH3:23])[CH3:22])[CH:10]([OH:19])[CH2:11][CH2:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 138931534-t-Butyloxycarbonylamino-3-hydroxy-6-methyl-1-phenylheptane

Product 1

HCID 200441484-Amino-3-hydroxy-6-methyl-1-phenylheptane hydrochloride

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The resultant compound of Example 1 (87 mg, 0.27 mmol) was dissolved in methanol (1 ml) and was treated with methanolic HCl (5 ml of 0.75M). After 15 hours the solution was evaporated to provide the desired compound as a glass (71 mg) which was used without further purification.

Workup

  1. customAfter 15 hours the solution was evaporated

Sources & evidence

ORD record
ord-906dd61b2f37435788b58d762f0e206a
Source dataset
uspto-grants-1987_03
Patent number
US04652551

Reaction notes

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