Methyl chloroformate → CARBAMIC ACID, (3-ACETYLPHENYL)-, METHYL ESTER

HRID 1906842Notes

Reaction equation

HRID 1906842 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]([C:8](=[O:10])[CH3:9])[CH:5]=[CH:6][CH:7]=1.C(N(C(C)C)CC)(C)C.Cl[C:21]([O:23][CH3:24])=[O:22]>ClCCl>[C:8]([C:4]1[CH:3]=[C:2]([NH:1][C:21](=[O:22])[O:23][CH3:24])[CH:7]=[CH:6][CH:5]=1)(=[O:10])[CH3:9]

Participants

5

Reactant 3

HCID 6586Methyl chloroformateHCID 74173'-AminoacetophenoneHCID 81531Diisopropylethylamine

Product 1

HCID 4049280CARBAMIC ACID, (3-ACETYLPHENYL)-, METHYL ESTER

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

A mixture of m-aminoacetophenone, diisopropylethylamine, methyl chloroformate and dichloromethane was reacted as described in Example 1, giving 33.4 g of (3-acetylphenyl)carbamic acid, methyl ester.

Workup

  1. customwas reacted

Sources & evidence

ORD record
ord-4e7b9e104ff64fef9644544b8c32a0e3
Source dataset
uspto-grants-1987_03
Patent number
US04654347

Reaction notes

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