Hydrogen Bromide → HCID 131715089, compound

HRID 1906904Notes

Reaction equation

HRID 1906904 reaction equation
[NH:1]([CH2:15][CH:16]([CH:18]1[CH2:23][CH2:22][C:21]2[CH:24]=[CH:25][CH:26]=[CH:27][C:20]=2[O:19]1)[OH:17])[CH2:2][CH:3]([CH:5]1[CH2:10][CH2:9][C:8]2[CH:11]=[CH:12][CH:13]=[CH:14][C:7]=2[O:6]1)[OH:4].[BrH:28]>CC(O)C>[BrH:28].[NH:1]([CH2:2][CH:3]([CH:5]1[CH2:10][CH2:9][C:8]2[CH:11]=[CH:12][CH:13]=[CH:14][C:7]=2[O:6]1)[OH:4])[CH2:15][CH:16]([CH:18]1[CH2:23][CH2:22][C:21]2[CH:24]=[CH:25][CH:26]=[CH:27][C:20]=2[O:19]1)[OH:17]

Participants

4

Reactant 2

HCID 260Hydrogen BromideHCID 1304802,2'-Azanediylbis[1-(3,4-dihydro-2H-1-benzopyran-2-yl)ethan-1-ol]

Product 1

HCID 131715089HCID 131715089, compound

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent2×

Procedure

To a stirred solution of 1 part of (A+A+)-α,α'-[iminobis(methylene)]bis[3,4-dihydro-2H-1-benzopyran-2-methanol] in 16 parts of 2-propanol were added dropwise 8 parts of 2-propanol saturated with hydrogen bromide. The product was filtered off and crystallized from 2-propanol. The product was filtered off and dried, yielding 0.8 parts of (A+A+)-α,α'-[iminobis(methylene)]bis[3,4-dihydro-2H-1-benzopyran-2-methanol]hydrobromide; mp. 236.5° C.; [α]589 =+114.53° (c=1% CH3OH) (compound 142).

Workup

  1. filtrationThe product was filtered off
  2. customcrystallized from 2-propanol
  3. filtrationThe product was filtered off
  4. customdried

Sources & evidence

ORD record
ord-ac6e87974606407cb67a2a85bedac4a1
Source dataset
uspto-grants-1987_03
Patent number
US04654362

Reaction notes

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